bio-hi-c-analysis-matrix-operations

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Balance, normalize, and transform Hi-C contact matrices using cooler and cooltools. Apply iterative correction (ICE), compute expected values, and generate observed/expected matrices. Use when normalizing or transforming Hi-C matrices.

tools-only By tools-only schedule Updated 2/14/2026

Skill instructions (SKILL.md) could not be loaded from local cache or raw GitHub repository.

Install via CLI
npx skills add https://github.com/tools-only/X-Skills --skill bio-hi-c-analysis-matrix-operations
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