bio-tumor-fraction-estimation

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Estimates circulating tumor DNA fraction from shallow whole-genome sequencing using ichorCNA. Detects copy number alterations via HMM segmentation and calculates ctDNA percentage. Requires 0.1-1x sWGS coverage. Use when quantifying tumor burden from liquid biopsy or monitoring treatment response.

tools-only By tools-only schedule Updated 2/14/2026
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Install via CLI
npx skills add https://github.com/tools-only/X-Skills --skill bio-tumor-fraction-estimation
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Occupations
Medical Scientists Except Epidemiologists
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