add-omics-runtime-pack

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Audit or refresh a curated pack of eight high-signal omics runtime skills in a BioClaw installation. Use when the user wants stronger built-in guidance for common omics analyses inside agent containers without changing BioClaw source code. Ensures the eight runtime skill folders exist under `container/skills/` with the expected flat file layout.

Runchuan-BU By Runchuan-BU schedule Updated 3/22/2026

name: add-omics-runtime-pack description: Audit or refresh a curated pack of eight high-signal omics runtime skills in a BioClaw installation. Use when the user wants stronger built-in guidance for common omics analyses inside agent containers without changing BioClaw source code. Ensures the eight runtime skill folders exist under container/skills/ with the expected flat file layout. disable-model-invocation: true

Add Omics Runtime Pack

This skill verifies that eight strong runtime skills are present under container/skills/ for common BioClaw analysis tasks.

What This Adds

  • container/skills/scrna-preprocessing-clustering/
  • container/skills/cell-annotation/
  • container/skills/chip-seq/
  • container/skills/atac-seq/
  • container/skills/differential-expression/
  • container/skills/proteomics/
  • container/skills/metagenomics/
  • container/skills/structural-biology/

Each runtime skill must contain only root-level files:

  • SKILL.md
  • technical_reference.md
  • commands_and_thresholds.md

What This Must Not Change

  • Do not modify src/, container/agent-runner/, Dockerfile, or any application code.
  • Do not modify src/container-runner.ts.
  • Do not add Python packages, R packages, or other dependencies.
  • Do not add nested references/ directories under container/skills/<skill>/.

The contribution is delivered as runtime skill content plus this installer skill, without any source-code changes.

Why The Runtime Skills Must Stay Flat

BioClaw syncs container/skills/<skill>/ into /home/node/.claude/skills/<skill>/ inside the container, but the sync only copies the first directory level.

That means:

  • container/skills/<skill>/SKILL.md will sync
  • container/skills/<skill>/technical_reference.md will sync
  • container/skills/<skill>/commands_and_thresholds.md will sync
  • container/skills/<skill>/references/... will not sync

So every installed runtime skill must be flat.

Runtime Skill Source Of Truth

The runtime-ready versions now live directly in:

container/skills/

Treat those directories as the source of truth. Do not recreate alternate copies under .claude/skills/.

Implementation Steps

Run all steps directly. Only pause if one of the target runtime skill directories already exists and appears user-modified.

1. Verify Current State

Check:

pwd
ls -la container/skills
for skill in \
  scrna-preprocessing-clustering \
  cell-annotation \
  chip-seq \
  atac-seq \
  differential-expression \
  proteomics \
  metagenomics \
  structural-biology
do
  test -e "container/skills/$skill" && echo "$skill already exists" || echo "$skill missing"
done

If any target directory already exists, inspect it before changing anything.

2. Create Or Update The Eight Runtime Skill Directories

For each skill listed below, ensure container/skills/<skill>/ exists and contains exactly the three required root-level files.

Runtime skill Required files
scrna-preprocessing-clustering SKILL.md, technical_reference.md, commands_and_thresholds.md
cell-annotation SKILL.md, technical_reference.md, commands_and_thresholds.md
chip-seq SKILL.md, technical_reference.md, commands_and_thresholds.md
atac-seq SKILL.md, technical_reference.md, commands_and_thresholds.md
differential-expression SKILL.md, technical_reference.md, commands_and_thresholds.md
proteomics SKILL.md, technical_reference.md, commands_and_thresholds.md
metagenomics SKILL.md, technical_reference.md, commands_and_thresholds.md
structural-biology SKILL.md, technical_reference.md, commands_and_thresholds.md

Do not invent alternate content unless the committed runtime files clearly conflict with the current repository state.

3. Preserve The Runtime-Ready Shape

For every installed runtime skill:

  • keep only the three root-level files above
  • do not create README.md
  • do not create nested references/
  • keep the relative links in SKILL.md pointing to technical_reference.md and commands_and_thresholds.md

4. Validate The Installed Pack

Run these checks:

find container/skills -maxdepth 2 -type f | sort
find container/skills -maxdepth 3 -type d -name references

The second command should produce no output for the eight installed skills.

Also confirm that no duplicate copy of the runtime pack remains under .claude/skills/add-omics-runtime-pack/.

Also confirm no external-path residue remains:

grep -RniE "/Users/|omics-skills-repo-template|bioSkills-main|OpenClaw-Medical-Skills-main|claude-scientific-skills-main" \
  container/skills/scrna-preprocessing-clustering \
  container/skills/cell-annotation \
  container/skills/chip-seq \
  container/skills/atac-seq \
  container/skills/differential-expression \
  container/skills/proteomics \
  container/skills/metagenomics \
  container/skills/structural-biology

That search should return no matches.

5. Report The Result

Summarize:

  • which runtime skill directories were created
  • whether all eight contain exactly the three required files
  • whether any pre-existing directories needed conflict resolution
  • that no source files were modified
Install via CLI
npx skills add https://github.com/Runchuan-BU/BioClaw --skill add-omics-runtime-pack
Repository Details
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navigation Branch main
article Path SKILL.md
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