By name: clawbio-pharmgx-reporter
version: 0.1.0
description: Pharmacogenomic report from DTC genetic data (23andMe/AncestryDNA)
author: Manuel Corpas
license: MIT
tags:
pharmacogenomics
CPIC
DTC-genetics
precision-medicine
inputs:
name: input
type: file
format: [23andme, ancestrydna, tsv]
description: Raw genetic data file from 23andMe or AncestryDNA
outputs:
name: report
type: file
format: markdown
description: Pharmacogenomic report with gene profiles and drug recommendations
metadata:
openclaw:
category: bioinformatics
homepage: https://github.com/ClawBio/ClawBio
min_python: "3.9"
dependencies: []
🦖 PharmGx Reporter
Generate a pharmacogenomic report from consumer genetic data (23andMe, AncestryDNA).
What it does
Parses raw genetic data files (auto-detects 23andMe or AncestryDNA format)
Extracts 31 pharmacogenomic SNPs across 12 genes
Calls star alleles and determines metabolizer phenotypes
Looks up CPIC drug recommendations for 51 medications
Generates a markdown report with gene profiles, drug tables, and alerts
Genes covered
CYP2C19, CYP2D6, CYP2C9, VKORC1, SLCO1B1, DPYD, TPMT, UGT1A1, CYP3A5, CYP2B6, NUDT15, CYP1A2
Drug classes
Antiplatelet, opioids, statins, anticoagulants, PPIs, antidepressants (TCAs, SSRIs, SNRIs), antipsychotics, NSAIDs, oncology, immunosuppressants, antivirals
Usage
python pharmgx_reporter.py --input patient_data.txt --output report
Disclaimer
This tool is for research and educational purposes only. It is NOT a diagnostic device. Always consult a healthcare professional before making any medication decisions.