interproscan-pipeline

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Predict protein domain families and functional annotation using InterProScan. Input a protein sequence and receive domain architecture, Gene Ontology (GO) terms, pathway annotations, and cross-references to protein databases including Pfam, SMART, PANTHER, and CDD.

AGI4Sci By AGI4Sci schedule Updated 5/3/2026

name: InterProScan Pipeline description: Predict protein domain families and functional annotation using InterProScan. Input a protein sequence and receive domain architecture, Gene Ontology (GO) terms, pathway annotations, and cross-references to protein databases including Pfam, SMART, PANTHER, and CDD. metadata: scpToolId: interproscan_pipeline scpCategory: life_science scpType: compute_tool provider: 上海人工智能实验室

InterProScan Pipeline

Overview

Performs comprehensive protein domain and functional annotation by scanning against multiple protein family databases using InterProScan methodology.

MCP Invocation

toolId: interproscan_pipeline
action: annotate
params:
  sequence?: string   # Amino acid sequence (FASTA format or raw)
  databases?: string[] # Optional: specific databases to search
  go_annotation?: boolean # Optional: include GO term annotation

Local Description

网页端调用: https://scphub.intern-ai.org.cn/skill/interproscan_pipeline

下载说明: 本地为 SKILL.md 资源定义,工具执行由 SCP Hub 远程服务提供。需配置 openteam.json → integrations.scpHub.apiKey

Output

  • Domain architectures with coordinates
  • Database matches (Pfam, SMART, PANTHER, CDD, InterPro)
  • GO term annotations (Biological Process, Molecular Function, Cellular Component)
  • KEGG/Reactome pathway associations
  • Protein family classification
Install via CLI
npx skills add https://github.com/AGI4Sci/SciForge --skill interproscan-pipeline
Repository Details
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article Path SKILL.md
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